Use the "Tubing Selection Guide" below to help you select the appropriate tubing for your application. The Chemical Compatibility guide and the chemical resistance summary in the table below are only guidelines. Chemical resistance and tubing wear may vary according to use—always test the tubing you select under the actual conditions.
Tubing Selection Guide
Chemical Resistance Classifications
A—No damage after 30 days of constant exposure.
B—Little or no damage after 30 days of constant exposure.
C—Some effect after 7 days of constant exposure. Effects may include: cracking, crazing, loss of strength, discoloration, softening, or swelling. Softening and swelling are reversible in some cases.
D—Not recommended for continuous use. Immediate damage may occur.
"_" Test data unavailable or not applicable.
| Formulation | Operating temperature |
Resin certification(s) |
Durometer | Chemical resistance summary | Permeability (approx)† Units: {cc-mmsec-cm2-cm Hg } x 10-10 |
||||||||
| Acids, weak |
Acids, strong |
Bases, weak |
Bases, strong |
Ozone | UV light |
CO2 | H2 | O2 | N2 | ||||
| Bev-A-Line® IV | -60 to 160°F (-51 to 71°C) |
FDA, USP, USDA, | 80 (D) | B | D | B | B | D | — | — | — | — | — |
| Bev-A-Line® V | -60 to 200°F (-51 to 93°C)* |
National Formulary | 80 (D) | B | B | B | B | D | — | — | — | — | — |
| Bev-A-Line® XX | -60 to 160°F (-51 to 71°C) |
FDA*, NSF* | 55 (D) | C | D | C | D | C | A | — | — | — | — |
| C-FLEX® | -100 to 275°F (-73 to 135°C) |
FDA, USP, USDA, GMP | 50 (A) | A | A | A | A | — | B | — | — | 150 | — |
| Chemfluor®367 | -400 to 450°F (-240 to 260°C) |
FDA | 58 (A) | A | A | A | A | A | — | — | — | — | — |
| Copper | -60 to 400°F (-53 to 204°C) |
None | — | D | D | C | C | A | A | — | — | — | — |
| EPDM food-grade; PTFE-lined; wire-reinforced |
-40 to 300°F (-40 to 148°C) |
FDA, USDA, 3A | — | A | B | A | A | — | — | — | — | — | — |
| ETFE | -150 to 302°F (-101 to 150°C) |
GMP | 75 (D) | A | A | A | A | A | A | — | — | — | — |
| FEP | -454 to 400°F (-270 to 205°C) |
FDA, USP, GMP | 55 (D) | A | A | A | A | A | A | 5.9 | 1.3 | 14 | 2.0 |
| Gum rubber | -15 to 158°F (-26 to 70°C) |
GMP | 35 (A) | A | D | A | B | C | D | 1311 | 492 | 307 | 118 |
| Hypalon® | 40 to 220°F (4 to 104°C) |
None | 70 (D) | — | A | — | — | — | — | — | — | — | — |
| Kynar® | -40 to 260°F (-40 to 127°C) |
FDA, USP, USDA | 80 (D) | A | A | A | A | A | A | — | — | — | — |
| MFA | -103 to 482°F (-75 to 250°C) |
USP | 59 (D) | A | A | A | A | A | A | — | — | — | — |
| Norprene® | -75 to 275°F (-60 to 135°C) |
GMP | 61 (A) | A | B | A | C | A | B | 1200 | — | 80 | 200 |
| Norprene® food-grade | -60 to 275°F (-51 to 135°C) |
FDA, NSF, GMP | 61 (A) | A | B | A | C | A | B | 1200 | — | 80 | 200 |
| Norprene® pressure | -60 to 275°F (-51 to 135°C) |
FDA, 3A, NSF | 61 (A) | A | B | A | C | A | B | 1200 | — | 80 | 200 |
| Nylon | -60 to 200°F (-51 to 93°C) |
None | — | A | D | A | C | C | D | 20 | 19 | 5.4 | 1.1 |
| PEEK | Up to 212°F (Up to 100°C) |
None | — | A | A | A | A | A | A | — | — | — | — |
| PFA | -320 to 500°F (-195 to 260°C) |
FDA, USP, GMP | 60 (D) | A | A | A | A | A | A | — | — | — | — |
| PFA-450 high-purity | -320 to 500°F (-195 to 260°C) |
FDA, GMP | 60 (D) | A | A | A | A | A | A | — | — | — | — |
| PharMed® | -75 to 275°F (-59 to 135°C) |
FDA, USP, NSF, GMP | 64 (A) | A | B | A | C | A | B | 1200 | — | 80 | 200 |
| Polyethylene | -100 to 175°F (-73 to 80°C) |
FDA, USDA | 50 (D) | A | D | B | B | B | A | 280 | — | 60 | 20 |
| Polyethylene, FEP-lined |
-100 to 175°F (-73 to 80°C) |
FDA, GMP | — | A | A | A | A | A | A | 5.9* | 1.3* | 14* | 2.0* |
| Polyimide | -418 to 896°F (-250 to 480°C) |
USP, NEMA | — | A | A | A | A | A | A | — | — | — | — |
| Polypropylene | 32 to 250°F (0 to 121°C) |
FDA, USDA | 75 (D) | A | D | B | B | C | D | 90 | — | 25 | 4 |
| Polyurethane (clear, aqua-tint) |
-40 to 180°F (-40 to 82°C) |
None | 95 (A) | B | D | B | B | A | — | 395 | 66 | 10.5 | 17.1 |
| Polyurethane (red, green, blue, black) |
-70 to 185°F (-57 to 85°C) |
None | 95 (A) | B | D | B | B | A | — | 395 | 66 | 10.5 | 17.1 |
| PTFE | -400 to 500°F (-240 to 260°C) |
FDA, USP, GMP | 50 (D) | A | A | A | A | A | A | 6.8 | — | — | 1.0 |
| PTFE color-coded |
-400 to 500°F (-240 to 260°C) |
None | 50 (D) | A | A | A | A | A | A | 6.8 | — | — | 1.0 |
| PVC | 10 to 140°F (-12 to 60°C) |
None | 65 (A) | A | A | A | A | A | A | 6.8 | — | — | 1.0 |
| PVC Bubble® | -5 to 180°F (-21 to 82°C) |
None | 55 (A) | A | D | A | D | B | D | 1305 | — | 1345 | — |
| PVC food-grade | 10 to 140°F (-12 to 60°C) |
FDA, 3A, USDA | 65 (A) | A | A | A | A | A | A | 6.8 | — | — | 1.0 |
| PVC reinforced | -5 to 180°F (-21 to 82°C) |
FDA, USDA, NSF, 3A | 65 (A) | A | D | A | A | B | D | 36 | — | 36 | — |
| PVC wire-reinforced |
25 to 150°F (-4 to 65°C) |
FDA, USDA, 3A, NSF | 70 (A) | A | D | A | A | B | D | 36 | — | 36 | — |
| Silicone, peroxide-cured |
-60 to 460°F (-51 to 238°C) |
FDA, USP, GMP | 50 (A) | B | D | A | A | A | — | 20,132 | 6579 | 7961 | 2763 |
| Silicone, platinum-cured |
-60 to 460°F (-51 to 238°C) |
FDA, USP, USDA, GMP | 50 (A) | B | D | A | A | A | — | 20,132 | 6579 | 7961 | 2763 |
| Silicone reinforced, peroxide |
-60 to 400°F (-51 to 204°C) |
FDA, USP, GMP | 60 (A) | B | D | A | A | A | — | 20,132 | 6579 | 7961 | 2763 |
| Stainless steel, 316 | -65 to 550°F (-53 to 289°C) |
None | — | A | B | A | C | A | A | — | — | — | — |
| Tygon®, FEP-lined |
-40 to 180°F (-40 to 82°C) |
FDA*, USP*, GMP | 67 (A) | A | A | A | A | B | B | 5.9* | 1.3* | 14* | 2.0* |
| Tygon® fuel/lubricant |
-35 to 165°F (-37 to 74°C) |
GMP | 57 (A) | B | C | C | D | A | A | 100 | — | 12 | 22 |
| Tygon® food/beverage |
-49 to 165°F (-45 to 74°C) |
FDA, NSF, 3A | 63 (A) | A | B | A | B | B | D | 270 | — | 30 | 60 |
| Tygon® high-purity |
-94 to 125°F (-70 to 52°C) |
FDA, USP, GMP | 72 (A) | A | C | A | A | B | B | 745 | — | 135 | 45 |
| Tygon® high-purity reinforced |
-94 to 125°F (-70 to 52°C) |
FDA, NSF, GMP | 72 (A) | A | C | A | A | B | B | 745 | — | 135 | 45 |
| Tygon® lab; vacuum |
-58 to 165°F (-50 to 74°C) |
FDA, GMP | 55 (A) | A | D | A | D | B | D | 360 | — | 40 | 80 |
| Tygon® LFL |
-58 to 165°F (-50 to 74°C) |
FDA, USP, GMP | 56 (A) | A | A | A | B | — | — | — | — | — | — |
| Tygon® pressure |
-47 to 165°F (-44 to 74°C) |
FDA, 3A, NSF | 65 (A) | A | A | B | A | — | — | 2700 | — | 600 | 300 |
| Tygon® sanitary silicone pres. |
-112 to 320°F (-51 to 160°C) |
FDA, USP, NSF, GMP | 70 (A) | B | D | A | A | A | — | — | — | — | — |
| Tygon® silicone |
-112 to 392°F (-80 to 200°C) |
FDA, USP, NSF, GMP | 50 (A) | A | C | A | A | B | B | — | — | — | — |
| Tygon® ultra chemical-resistant |
-108 to 125°F (-78 to 52°C) |
GMP | 72 (A) | A | C | A | A | B | B | 4840 | — | 980 | 350 |
| Tygothane® pressure |
-100 to 180°F (-73 to 82°C) |
FDA, NSF | 82 (A) | C | C | B | D | A | — | 1680 | — | 180 | 60 |
| Vinyl | -45 to 180°F (-43 to 82°C) |
GMP | 67 (A) | A | D | A | A | C | D | 360 | — | 40 | 80 |
| Viton® | -25 to 400°F (-32 to 204°C) |
GMP | 75 (A) | A | A | C | D | A | A | 79 | — | 15 | 4.3 |
*Based on liner
†At 25°C
Bev-A-Line—Reg TM Thermoplastic Processes, Inc.
Bubble—Reg TM Sherwood Medical Industries Inc.
Chemfluor, Norprene, PharMed, Tygon, Tygothane—Reg TM Norton Performance Plastics Corp.
C-FLEX—Reg TM Consolidated Polymer Technologies, Inc.
Hypalon, Viton—Reg TM DuPont Dow Elastomers L.L.C.
Kynar, Superflex—Reg TM Elf Atochem North America
PTFE—Reg TM E. I. DuPont de Nemours & Co.
Reference source: http://www.coleparmer.com/TechLibraryArticle/700
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